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Yi Xia Selected Research

NUPR1 inhibitor ZZW-115

1/2021Response to the Letter to the editor regarding "Targeting NUPR1 with the small compound ZZW-115 is an efficient strategy to treat hepatocellular carcinoma" by Jiong Lin.
1/2020ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.
1/2020Targeting NUPR1 with the small compound ZZW-115 is an efficient strategy to treat hepatocellular carcinoma.
11/2019Targeting the Stress-Induced Protein NUPR1 to Treat Pancreatic Adenocarcinoma.
1/2019Ligand-based design identifies a potent NUPR1 inhibitor exerting anticancer activity via necroptosis.

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Yi Xia Research Topics

Disease

51Neoplasms (Cancer)
10/2021 - 11/2004
27Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
03/2022 - 04/2007
24Lymphoma (Lymphomas)
11/2021 - 04/2006
15B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
04/2022 - 04/2007
8Non-Hodgkin Lymphoma (Lymphosarcoma)
04/2020 - 11/2004
8Pancreatic Neoplasms (Pancreatic Cancer)
01/2019 - 02/2009
7Hodgkin Disease (Hodgkin's Disease)
01/2022 - 03/2013
6Neoplasm Metastasis (Metastasis)
08/2021 - 12/2006
6Esophageal Squamous Cell Carcinoma
01/2021 - 01/2017
5Peripheral T-Cell Lymphoma (Lymphoma, T Cell, Peripheral)
01/2022 - 04/2007
5Disease Progression
12/2019 - 12/2006
5Infections
01/2019 - 01/2005
4Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
11/2022 - 04/2007
4Hepatocellular Carcinoma (Hepatoma)
10/2021 - 01/2017
4Vomiting
10/2019 - 08/2007
4B-Cell Lymphoma (Lymphoma, B Cell)
01/2019 - 08/2011
4Burkitt Lymphoma (Burkitt's Lymphoma)
01/2016 - 04/2007
4Parkinson Disease (Parkinson's Disease)
02/2014 - 10/2011
4Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
03/2010 - 10/2006
3Inflammation (Inflammations)
11/2021 - 05/2012
3Adenocarcinoma
10/2021 - 01/2019
3Breast Neoplasms (Breast Cancer)
01/2020 - 01/2014
3Dermatitis
10/2019 - 03/2017
3Fatigue
10/2019 - 03/2017
3T-Cell Lymphoma (Lymphoma, T Cell)
01/2019 - 05/2009
3Carcinoma (Carcinomatosis)
06/2018 - 03/2017
3Neurodegenerative Diseases (Neurodegenerative Disease)
02/2014 - 05/2012
2Neutropenia
11/2022 - 06/2018
2Marginal Zone B-Cell Lymphoma (MALT Lymphoma)
01/2022 - 11/2017
2Alzheimer Disease (Alzheimer's Disease)
10/2021 - 09/2013
2Extranodal NK-T-Cell Lymphoma
02/2021 - 09/2015
2Waldenstrom Macroglobulinemia (Macroglobulinemia)
01/2020 - 05/2016
2Necrosis
01/2020 - 09/2018
2Emphysema
12/2019 - 11/2017
2Anemia
10/2019 - 01/2018
2Thrombocytopenia (Thrombopenia)
10/2019 - 06/2018
2Nausea
10/2019 - 08/2007
2Osteoporosis
07/2019 - 06/2009
2Hematologic Neoplasms (Hematological Malignancy)
04/2019 - 01/2016
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2019 - 01/2019
2Sepsis (Septicemia)
12/2018 - 01/2007
2Pneumonia (Pneumonitis)
06/2018 - 03/2017
2Euthyroid Sick Syndromes (Euthyroid Sick Syndrome)
01/2018 - 01/2017
2Cerebral Hemorrhage
01/2018 - 01/2007
2Nasopharyngeal Carcinoma
01/2017 - 01/2017

Drug/Important Bio-Agent (IBA)

13Pharmaceutical PreparationsIBA
01/2022 - 08/2007
13Rituximab (Mabthera)FDA Link
01/2021 - 02/2009
12Proteins (Proteins, Gene)FDA Link
10/2021 - 06/2012
9Biological ProductsIBA
04/2022 - 12/2012
9Biomarkers (Surrogate Marker)IBA
11/2021 - 10/2008
7GemcitabineFDA Link
01/2022 - 04/2010
6DNA (Deoxyribonucleic Acid)IBA
02/2021 - 05/2012
6Cisplatin (Platino)FDA LinkGeneric
04/2020 - 01/2017
5Intrinsically Disordered ProteinsIBA
10/2021 - 01/2019
5NUPR1 inhibitor ZZW-115IBA
01/2021 - 01/2019
5Cyclophosphamide (Cytoxan)FDA LinkGeneric
01/2020 - 05/2009
5Paclitaxel (Taxol)FDA LinkGeneric
10/2019 - 01/2017
4Immunoglobulins (Immunoglobulin)IBA
01/2022 - 01/2018
4Indicators and Reagents (Reagents)IBA
11/2021 - 06/2009
4Vitamin DFDA LinkGeneric
02/2021 - 04/2020
4MicroRNAs (MicroRNA)IBA
04/2020 - 10/2010
4AlbuminsIBA
04/2019 - 01/2016
4Doxorubicin (Adriamycin)FDA LinkGeneric
07/2016 - 05/2009
4Vincristine (Oncovin)FDA LinkGeneric
07/2016 - 05/2009
4NucleosidesIBA
01/2015 - 12/2010
3Methotrexate (Mexate)FDA LinkGeneric
03/2022 - 05/2009
3N- (2- amino- 5- fluorobenzyl)- 4- (N- (pyridine- 3- acrylyl)aminomethyl)benzamideIBA
01/2022 - 01/2020
3ParaproteinsIBA
01/2022 - 05/2016
3Inosine Diphosphate (IDP)IBA
10/2021 - 01/2019
3Immunoglobulin Heavy Chains (Immunoglobulin Heavy Chain)IBA
01/2020 - 01/2018
3Heat-Shock Proteins (Heat-Shock Protein)IBA
01/2020 - 01/2012
3L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
10/2019 - 01/2013
3Fluorouracil (Carac)FDA LinkGeneric
10/2019 - 03/2017
3Prednisone (Sone)FDA LinkGeneric
07/2016 - 06/2012
3AntibodiesIBA
01/2016 - 04/2007
3TriazolesIBA
01/2015 - 10/2009
3Brain-Derived Neurotrophic Factor (BDNF)IBA
02/2014 - 10/2011
3Nerve Growth Factors (Neurotrophins)IBA
02/2014 - 10/2011
2ibrutinibIBA
11/2022 - 10/2019
2Immune Checkpoint InhibitorsIBA
01/2022 - 01/2016
2Histone Deacetylase InhibitorsIBA
01/2022 - 01/2020
2liposomal doxorubicin (Doxil)FDA Link
01/2022 - 03/2013
2Vinorelbine (Navelbine)FDA LinkGeneric
01/2022 - 03/2013
2Dexamethasone (Maxidex)FDA LinkGeneric
01/2021 - 05/2009
2Oxaliplatin (Eloxatin)FDA LinkGeneric
01/2021 - 06/2018
2Messenger RNA (mRNA)IBA
08/2020 - 10/2018
2B7-H1 AntigenIBA
01/2020 - 10/2019
2Anti-Bacterial Agents (Antibiotics)IBA
01/2019 - 11/2017
2CytokinesIBA
09/2018 - 02/2016
2Carboplatin (JM8)FDA LinkGeneric
06/2018 - 12/2006
2Thyrotropin (Thyroid-Stimulating Hormone)FDA Link
01/2018 - 01/2017
2C-Reactive ProteinIBA
01/2017 - 01/2013
2LigandsIBA
01/2016 - 01/2015

Therapy/Procedure

29Therapeutics
11/2022 - 04/2006
18Drug Therapy (Chemotherapy)
01/2022 - 10/2005
11Radiotherapy
11/2021 - 12/2006
6Chemoradiotherapy
01/2021 - 03/2017
3Consolidation Chemotherapy
06/2018 - 07/2009
3VAP-cyclo protocol
10/2015 - 12/2007
2Catheters
01/2020 - 06/2016